| Indication |
- Treatment or prophylaxis of iron deficiency anaemia
|
| Preparations |
- Venofer® iron sucrose; 100 mg/5ml
- Cosmofer® iron dextran; 100 mg/2ml, 500 mg/10ml
- Ferrinject® ferric carboxymaltose; 100 mg/2ml, 500 mg/10ml
- Monofer® iron(III) isomaltoside 1000; 100 mg/ml
- Rienso® ferumoxytol 30 mg/ml
- Prescribe by brand
|
| Contraindications |
- Iron overload, anaemia not caused by iron deficiency
- Hypersensitivity to iron or to any of the excipients
- Pregnancy first trimester
|
| Cautions |
- Monitor iron stores. Aim for a ferritin 100-500 ng/ml and TSAT >20%
- Anaphylactic reactions can occur with all preparations. A test dose is recommended before the first dose; and before each dose with Iron Dextran. Care in asthmatic patients
- Parenteral iron must be used with caution in cases of acute or chronic infection. It is recommended that the administration of IV iron is stopped in patients with on-going bacteraemia
|
| Side-effects |
- Metallic taste, hypotension, fever and shivering, allergic reactions
|
| Dose |
- A test dose is required before the first dose
- Patients on HD: varies from 20 mg each dialysis to 100 mg weekly, fortnightly or monthly
- Patients not on HD: varies between centres. Examples include 100 mg fortnightly for 3 doses or 1g as a total dose infusion
|
| Dose in renal impairment |
- As in normal renal function, not dialysed
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| Interactions |
- Reduced absorption of oral iron, dimercaprol – avoid concomitant use
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| How to Prescribe |
View Details |
| Patient comment |
- Preparation used and dose given varies according to local protocols
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